Elixirs and Flavoring Plants

ELIXIR OF CINCHONA AND HYPOPHOSPHITES

Hypophosphite of calcium,......... 128 grains.
Hypophosphite of sodium,..... .... 128 grains.
Citric acid,.......................................... 30 grains.
Water,.......................................... 2 fluidounces.

Elixir of cinchona, ....... enough to make 16 fluidounces.

The citric acid and hypophosphites are to be dissolved in the water, and the solution mixed with enough elixir of cinchona to make sixteen fluidounces, and then filtered. Each fluidrachm contains one grain each of the hypophosphites of calcium and sodium. This formula is identical in strength with that of the National Formulary.

89. DETANNATED ELIXIR OF CINCHONA.

Detannated tincture of cinchona,.......................................
2 fluidounces.
Aromatic spirits,........................2 fluidounces.
Syrup,........................................... 6 fluidounces.
Purified talcum,......................... .... 120 grains.
Water, enough to make...........16 fluidounces.

Mix the liquids, allow the mixture to stand twenty-four hours or longer, then add the purified talcum. Shake well together, and filter.
Each fluidounce represents fourteen grains of yellow cinchona. This formula is similar to that of the National Formulary, and the product is of the same strength.

90. ELIXIR OR CINCHONINE.

Cinchonine (alkaloid),............. .... 256 grains.
Simple elixir, phosphoric acid (U. S. P., 1872),..........................of each a sufficient quantity.

Triturate the powdered cinchonine in a mortar with three fluidounces of simple elixir, and dissolve it by the gradual addition of a sufficient amount of phosphoric acid; then mix this solution with a sufficient amount of simple elixir to make the whole measure sixteen fluidounces, and filter if necessary.
Each fluidrachm (teaspoonful) of the finished elixir contains of phosphate of cinchonine an amount which is equivalent to two grains of cinchonine.

91. ELIXIR OF PHOSPHATES OF CINCHONINE AND
CINCHONIDINE.

Mix equal amounts, by measure, of elixir of phosphate of cinchonine and elixir of phosphate of cinchonidine.
Each fluidrachm of the finished elixir contains of phosphate of cinchonidine an amount which is equivalent to one-half grain of cinchonidine, and of phosphate of cinchonine an amount which is equivalent to one grain of cinchonine

92. ELIXIR OF PHOSPHATES OF CINCHONINE AND STRYCHNINE

Strychnine,....................................... 1 grains.

Elixir of phosphate of cinchonine, 16 fluidounces.

Phosphoric acid (U. S. P., 1872), ............................a sufficient quantity.

Triturate the powdered strychnine in a mortar with sufficient phosphoric acid, gradually added, to effect its solution; then add the elixir of phosphate of cinchonine. and filter if necessary.
Each fluidrachm (teaspoonful) of the finished elixir contains of phosphates of cinchonine and strychnine an amount which is equivalent to two grains of cinchonine and one-hundredth of a grain of strychnine.

93. ELIXIR OF PHOSPHATE OF CINCHONIDINE.
(ELIXIR OF PHOSPHATE OF CINCHONIDIA. ELIXIR OF CINCHONIDIA.)

Cinchonidine (alkaloid),.............. 128 grains.
Simple elixir, phosphoric acid (U. S. P., 1872), .........................of each a sufficient quantity.

Powder the cinchonidine, and triturate it in a mortar with two fluidounces of simple elixir. When a smooth, creamy mixture results, continue the trituration, and gradually add of phosphoric acid an amount sufficient to dissolve the cinchonidine; then mix this solution with a sufficient amount of simple elixir to make the whole measure sixteen fluidounces, and filter if necessary.
Each fluidrachm (teaspoonful) of the finished elixir contain of phosphate of cinchonidine an amount which is equivalent to one grain of cinchonidine.

94. ELIXIR OF PHOSPHATES OF CINCHONIDINE, CINCHONINE,
AND STRYCHNINE.
(ELIXIR OF CINCHONIDIA, CINCHONIA, AND STRYCHNIA.)

Strychnine,....................................... 1 grains.

Elixir of phosphates of cinchonidine and cinchonine,....................16 fluidounces.
Phosphoric acid (U. S. P., 1872), .....................................a sufficient quantity.

Triturate the powdered strychnine in a mortar with sufficient phosphoric acid to effect its solution, then add the elixir of phosphates of cinchonidine and cinchonine, and filter if necessary.
Each fluidrachm (teaspoonful) of the finished elixir contains of phosphates of cinchonidine, cinchonine, and strychnine an amount which is equivalent to one-half grain of cinchonidine, one grain of cinchonine, and one-hundredth of a grain of strychnine.

95. ELIXIR OF PHOSPHATES OF CINCHONIDINE AND
STRYCHNINE.
(ELIXIR OF CINCHONIDIA AND STRYCHNIA.)

Strychnine,....................................... 1 grains.

Elixir of phosphate of cinchonidine,16 fluidounces.
Phosphoric acid (U. S. P., 1872), .....................................a sufficient quantity.

Triturate the powdered strychnine in a mortar with sufficient phosphoric acid to effect its solution; then add the elixir of
cinchonidine, and filter if necessary.
Each fluidrachm (teaspoonful) of the finished elixir contains of phosphates of cinchonidine and strychnine an amount which is equivalent to one grain of cinchonidine and one-hundredth of a grain of strychnine.

96. ELIXIR OF ACETATE OF CHINOIDINE.
(ELIXIR OF CHINOIDINE.)

Chinoidine,..................................... 256 grains.
Distilled water,...........................4 fluidounces.

Acetic acid, simple elixir, of each a sufficient quantity.
Powder the chinoidine and dissolve it in the distilled water by the addition of a sufficient amount of acetic acid, then add of simple elixir until sixteen fluidounces are produced, and filter.
Each fluidrachm (teaspoonful) of the finished elixir contains two grains of chinoidine.

97. COMPOUND ELIXIR OF CHINOIDINE.

Elixir of chinoidine,..................8 fluidounces.
Elixir of dandelion,................... 8 fluidounces.

Mix them together. This agrees, practically, with the formula adopted by the joint committee of the National College of Pharmacy and the Medical Society of the District of Columbia.
Each fluidrachm (teaspoonful) of the finished elixir contains one grain of chinoidine and represents about four minims of fluid extract of dandelion.

98. ELIXIR OF BISULPHATE OF QUININE.
(ELIXIR OF SULPHATE OF QUINIA.)

Sulphate of quinine,................. .... 128 grains.
Simple elixir,..............................16 fluidounces.
Dilute sulphuric acid,...............a sufficient quantity.

Mix the sulphate of quinine with four fluidounces of simple elixir, and add enough dilute sulphuric acid to effect its solution. Then add the remainder of the simple elixir, and filter if necessary.
Each fluidrachm (teaspoonful) of the finished elixir contains one grain of sulphate of quinine.
The addition of the excess of sulphuric acid actually produces bisulphate of quinine; hence the term elixir of bisulphate of quinine is admissible, although sulphate of quinine is employed.

99. ELIXIR OF HYDROBROMATE OF QUININE.
(ELIXIR OF BROMIDE OF QUINIA.)

Hydrobromate of quinine,........... 128 grains.

Simple elixir, hydrobromic acid, of each a sufficient quantity.
Mix the hydrobromate of quinine with the simple elixir, and cautiously add of hydrobromic acid an amount sufficient to effect its solution. Filter, if necessary.
Each fluidrachm (teaspoonful) of the finished elixir contains one grain of hydrobromate of quinine.
The term often used for this substance—”bromide of quinine” —is incorrect, since alkaloids combine bodily with acids.

100. ELIXIR OF PHOSPHATE OF QUININE.
(ELIXIR OF QUININE. ELIXIR OF PHOSPHATE OF QUINIA )

Quinine (alkaloid),........................ 128 grains.
Simple elixir, phosphoric acid (U. S. P., 1872),...............................of each a sufficient quantity.

Powder the quinine, and triturate it in a mortar with two fluid-ounces of simple elixir. When a smooth, creamy mixture results, continue the trituration, and gradually add of phosphoric acid an amount sufficient to dissolve the quinine. Then mix this solution with a sufficient amount of simple elixir to make the whole measure sixteen fluidounces.
Each fluidrachm (teaspoonful) of the finished elixir contains of phosphate of quinine an amount which is equivalent to one grain of quinine.

101. COMPOUND ELIXIR OF QUININE.

Sulphate of quinine,................. ...... 16 grains.
Sulphate of cinchonidine,................ 8 grains
Sulphate of cinchonine,.................... 8 grains
Aromatic elixir, .........................16 fluidounces.

Dissolve the alkaloidal salts in the aromatic elixir by agitating them together, and then filter. Each fluidounce contains one grain of sulphate of quinine and one-half grain each of the sulphates of cinchonidine and cinchonine. The above formula conforms in strength with that of the National Formulary.

102. ELIXIR OF PHOSPHATE OF QUININE AND CINCHONIDINE.

Elixir of phosphate of quinine and elixir of phosphate of cinchonidine,......... equal amounts by measure.
Mix them together.

Each fluidrachm (teaspoonful) of the finished elixir contains of phosphate of quinine and of phosphate of cinchonidine an amount which is equivalent to one-half grain each of quinine and of cinchonidine.

103. ELIXIR OF PHOSPHATE OF QUININE AND CINCHONINE.
(ELIXIR OF QUINIA AND CINCHONIA.)

Elixir of phosphate of quinine and
elixir of phosphate of cinchonine, .........of each equal amounts by measure.
Mix them together.

Each fluidrachm (teaspoonful) of the finished elixir contains of phosphate of quinine an amount which is equivalent to one-half grain of quinine, and of phosphate of cinchonine an amount which is equivalent to one grain of cinchonine.

104. ELIXIR OF PHOSPHATES OF QUININE, CINCHONIDINE,
AND CINCHONINE.

Elixir of phosphate of quinine, elixir of phosphate of cinchonidine, and elixir of phosphate of cinchonine, .........of each equal amounts by measure.
Mix them together.

Each fluidrachm (teaspoonful) of the finished elixir contains of phosphate of quinine an amount which is equivalent to one-third of a grain of quinine, and of phosphate of cinchonidine an amount which is equivalent to one-third of a grain of cinchonidine, and of phosphate of cinchonine an amount which is equal to two-thirds of a grain of cinchonine.

105. ELIXIR OF PHOSPHATE OF QUININE WITH CITRATE
OF PROTOXIDE OF IRON.
(ELIXIR OF PROTOXIDE OF IRON WITH QUINIA.
ELIXIR OF QUININE AND FERROUS PHOSPHATE.)

Elixir of protoxide of iron,.......8 fluidounces.
Elixir of phosphate of quinine,...8 fluidounces.
Mix them together.

Each fluidrachm (teaspoonful) of the finished elixir contains one-half grain of quinine, and as much citrate of protoxide of iron as corresponds with one grain of sulphate of iron. This elixir is not very stable.

106. ELIXIR OF PHOSPHATE OF QUININE WITH CITRATE
OF PROTOXIDE OF IRON AND STRYCHNINE.
(ELIXIR OF QUINIA AND PROTOXIDE OF IRON AND STRYCHNIA.
ELIXIR OF QUININE, FERROUS CITRATE, AND STRYCHNINE.)

Elixir of phosphate of quinine with citrate of protoxide of iron,....16 fluidounces.
Strychnine,....................................... 1 grains.
Acetic acid,.................................. a sufficient quantity.

Triturate the strychnine in a mortar, cautiously adding acetic acid in amount sufficient to effect its solution, and mix this with the elixir of phosphate of quinine and citrate of protoxide of iron.
Each fluidrachm (teaspoonful) of the finished elixir contains one-half grain of quinine, as much citrate of protoxide of iron as corresponds with one grain of sulphate of iron, and one-hundredth of a grain of strychnine.
The term " protoxide of iron " is a misnomer. See our remark concerning elixir of calisaya bark with protoxide of iron. This preparation is unstable.

107. ELIXIR OF PHOSPHATE OF QUININE AND STRYCHNINE.
(ELIXIR OF QUINIA AND STRYCHNIA.)

Quinine (alkaloid),........................ 128 grains.
Strychnine,...................................... 1 grains.
Simple elixir, phosphoric acid (U. S..P., 1872),.............................of each a sufficient quantity.

Triturate the powdered strychnine in a mortar with two fluidounces of simple elixir, and dissolve by addition of a sufficient amount of phosphoric acid. Now add the quinine (previously powdered), and then, continuing the trituration, gradually add of phosphoric acid an amount sufficient to dissolve the quinine. Then mix this solution with a sufficient amount of simple elixir to make the whole measure sixteen fluidounces, and filter if necessary.
Each fluidrachm (teaspoonful) of the finished elixir contains of phosphate of quinine and phosphate of strychnine an amount which is equivalent to one grain of quinine and one-hundredth of a grain of strychnine.

1O8. ELIXIR OF VALERIANATE OF QUININE.

Valerianate of quinine,............ ..... 128 grains
Simple elixir,..............................16 fluidounces.
Valerianic acid,.......................... a sufficient quantity.

Powder the valerianate of quinine in a mortar and gradually add the simple elixir. Then cautiously drop into the mixture valerianic acid sufficient to render the liquid transparent, stirring continually, and filter if necessary.
This formula conforms to that by Prof. C. Lewis Diehl (1872), read before the Louisville College of Pharmacy.
Each fluidrachm (teaspoonful) of the finished elixir contains one grain of valerianate of quinine.

109. ELIXIR OF VALERIANATE OF QUININE WITH STRYCHNINE.
(ELIXIR OF VALERIANATE OF QUINIA AND STRYCHNIA )

Elixir of valerianate of quinine,.......14 fluidounces.
Distilled water,2 fluidounces.
Strychnine,.... ........................................1 grains.
Valerianic acid,.......................... a sufficient quantity.

Powder the strychnine in a mortar and add the water, and then enough valerianic acid to effect the solution of the strychnine.
Lastly, add the simple elixir, and filter if necessary.
Each fluidrachm (teaspoonful) will contain about one grain of valerianate of quinine and one-hundredth of a grain of strychnine.
In former editions of our publication the proportion was onefiftieth of a grain of strychnine to each fluidrachm. In this edition we conform to the strength established by the National Formulary.




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