Elixirs and Flavoring Plants

ELIXIR OF COCA

110. ELIXIR OF COCA

Fluid extract of coca,..................2 fluidounces.
Simple elixir,..............................14 fluidounces.
Purified talcum,......................... .... 120 grains.

Triturate the fluid extract of coca with the purified talcum, and gradually add the elixir, shaking well together and agitating occasionally for twenty-four hours, then filter.
Each fluidrachm represents seven and one-half grains of coca.

111. ELIXIR OF CURAÇOA.

Syrup of Curaçoa,...................... .120 minims.
Orris root, powdered,...................... 30 grains.
Deodorized alcohol,..................4 fluidounces.
Citric acid,.......................................... 50 grains.
Syrup,........................................... 8 fluidounces.
Purified talcum,......................... ... 120 Grains.
Water,...........................enough to make 16 fluidounces.

Mix the syrup of Curaçoa with the alcohol, add the orris and purified talcum and three fluidounces of water. After twelve hours, agitating occasionally, pour the mixture on a wetted filter, returning the first portions of the filtrate until it runs clear, and follow the filtrate with enough water to make eight fluidounces in all. In this dissolve the citric acid, and finally add the syrup. This elixir is practically identical with that of the National Formulary, the proportions of ingredients being the same.

112. ELIXIR OF DANDELION.
(ELIXIR OF TARAXACUM.)

Fluid extract of dandelion,...... 2 fluidounces.
Simple elixir,..............................14 fluidounces.
Carbonate of magnesium,......a sufficient quantity.

Triturate the fluid extract of dandelion in a capacious mortar with carbonate of magnesium in amount sufficient to form a creamy mixture, then gradually add the simple elixir, stirring well, and filter.
Each fluidrachm of the finished elixir represents seven and one-half minims of fluid extract of dandelion.

113. COMPOUND ELIXIR OF DANDELION.
(COMPOUND ELIXIR OF TARAXACUM. )

Fluid extract of dandelion,.....................1 fluidounce.
Fluid extract of wild-cherry bark,........ fluidounce.
Fluid extract of gentian,.......................... fluidounce.
Fluid extract of bitter orange peel,..... fluidounce.
Fluid extract of cinnamon,..................... fluidounce.
Fluid extract of licorice,........................... fluidounce.
Powdered anise,........................................20 grains.
Powdered caraway,...................................20 grains.
Powdered coriander,................................20 grains.
Simple elixir,.........................................14 fluidounces.
Carbonate of magnesium,..................a sufficient quantity.

Triturate the mixed fluid extracts and powdered drugs in a capacious mortar with carbonate of magnesium in amount sufficient to form a creamy mixture, then gradually add the simple elixir, stirring well, and cover the mixture and permit it to macerate an hour, then filter it. This elixir was devised by Prof. P. C. Candidus, of Mobile, and the formula was presented at the meeting of the American Pharmaceutical Association, 1869. Prof. Candidus stated that this elixir completely masks the bitter taste of sulphate of quinine, and he recommended it as a vehicle for administering that substance. Since one of the ingredients is licorice (see elixir of glycyrrhizin), we may suppose that glycyrrhizin aids in overcoming the bitterness, and our remarks concerning quinine and glycyrrhizin should be applicable to this elixir. The formula we present does not materially vary from that offered by Prof. Candidus, excepting in the substitution of fluid extracts for crude drugs.

114. ELIXIR OF DANDELION WITH QUININE.
(ELIXIR OF TARAXACUM AND QUINIA.)

Elixir of dandelion,8 fluidounces.
Elixir of phosphate of quinine,8 fluidounces.
Mix them together.

Each fluidrachm (teaspoonful) of the finished elixir contains three and one-fourth minims of fluid extract of taraxacum and onehalf grain of quinine.
In the year 1873 Mr. James W. Long furnished the American Journal of Pharmacy with a process for making the foregoing preparation.

115. DAFFY’S ELIXIR.
(DILLY’S DAFFY; ELIXIR OF HEALTH.—New Dispensatory, 1770 )

Senna,.......................................... ........4 ounces
Guaiac wood,......................................2 ounces
Elecampane root,...............................2 ounces
Anise seed,..........................................2 ounces
Caraway seed,............................. ........2 ounces
Coriander seed,.......................... ........2 ounces
Licorice root,.......................................2 ounces
Raisins,........................................ ........8 ounces
Diluted alcohol,......................... ........... 6 pints

Reduce the drugs to a coarse powder, and mix them with the diluted alcohol. Then seed the raisins, chop them fine, add to the mixture, and macerate fourteen days, stirring the mixture thoroughly each day; then filter (Supplement to London Pharmacopoeia, 1821). A number of compounds have been offered as “Daffy’s Elixir,” and from among them we have selected the preceding.

116. ELIXIR OF DAMIANA.

Fluid extract of damiana,.........2 fluidounces.
Simple elixir,..............................16 fluidounces.
Alcohol,....................................... fluidounces.
Carbonate of magnesium,....... a sufficient quantity.

Triturate the fluid extract of damiana in a capacious mortar with carbonate of magnesium in amount sufficient to form a creamy mixture, then gradually add the simple elixir, stirring well, and filter.
Lastly, mix the filtrate with the alcohol.
Each fluidrachm of the finished elixir represents nine and one-half minims of fluid extract of damiana.

117. ELIXIR DEWBERRY COMPOUND.
(ELIXIR RUBI TRIVIALIS COMPOSITUM. )

Dewberry root,............................4 troyounces.
Nutgalls,..........................................4 drachms.
Kino,.................................................4 drachms.
Cinnamon,......................................2 drachms.
Cloves,......................................... ..... 1 drachm.
Capsicum,.......................................... 10 grains.
Tincture opium,........................ 1 fluidounce.
Essence peppermint,.................1 fluidrachms.
Brandy,.........................................32 fluidounces.
Sugar,........................................... 14 troyounces.

Reduce the drugs to a coarse powder, and macerate in the brandy for fourteen days, stirring the mixture thoroughly each day, then filter, and dissolve the sugar in the filtrate.
(New Remedies, 1880.)

118. ELIXIR OF EUCALYPTUS.

Fluid extract of eucalyptus,......2 fluidounces.
Simple elixir,..............................14 fluidounces.
Alcohol,....................................... fluidounce.
Carbonate of magnesium,....... a sufficient quantity.

Triturate the fluid extract of eucalyptus with carbonate of magnesium in sufficient amount to form a creamy mixture, then gradually add the simple elixir, and filter. Lastly, mix the alcohol with the filtrate.
Each fluidrachm of the finished preparation will contain such proportion of seven and one-half minims of fluid extract of eucalyptus as will dissolve in that amount of the menstruum. In our opinion, the proper menstruum for extracting the medicinal principles of eucalyptus is alcohol of specific gravity 0.820. The addition of water detracts from its value as a dissolving medium, in proportion to the amount of water present. Therefore elixir of eucalyptus does not represent the fluid extract of eucalyptus employed in making it.
The proportions of eucalyptus upon which the foregoing elixir was based will be found in the Druggists’ Circular, 1877.

119. COMPOUND ELIXIR OF EUCALYPTUS.

Fluid extract of eucalyptus,......2 fluidounces.
Fluid extract of licorice root,... fluidounce.
Fluid extract of wild cherry,.... fluidounce.
Simple elixir,..............................14 fluidounces.
Carbonate of magnesium,....... a sufficient quantity.

Mix the fluid extracts, and triturate them in a capacious mortar with carbonate of magnesium in amount sufficient to form a creamy mixture, then gradually add the simple elixir, stirring well, then filter.
Each fluidrachm of the finished elixir represents such an amount of seven and one-half minims of fluid extract of eucalyptus as will dissolve in one fluidrachm of the finished menstruum, and about two minims each of the fluid extracts of licorice root and wild cherry.
This preparation is intended as a pleasant mode of administering eucalyptus; but the proportion of eucalyptus represented is uncertain, owing to the fact that alcohol of specific gravity 0.820 is the proper solvent for the medicinal principles of the leaves. The formula we present is based upon ingredients suggested in the Druggists’ Circular, 1877.

120. ELIXIR DE GlARUS.

Myrrh,................................................ 90 grains.
Aloes,........................................... ...... 90 grains.
Cloves,......................................... .... 180 grains.
Nutmegs,......................................... 180 grains.
Saffron,........................................ .... 480 grains.
Cinnamon,...................................... 360 grains.
Alcohol,............................................... 12 pints.

Reduce the drugs to a coarse powder, mix this with the alcohol, and distill nine pints. Reserve this.

Maidenhair,................................4 troyounces.
Licorice root,............................... troyounce.
Figs,...............................................3 troyounces.

Infuse these in eight pints of boiling water, strain with expression, and dissolve in the liquid twelve avoirdupois pounds of sugar.
Equal parts, by weight, of this syrup and of the distilled spirit produce " elixir de garus," according to the Supplement to the London Pharmacopoeia, 1821.
This cumbersome and unscientific mixture, a relic of ancient polypharmacy, is happily nearly obsolete.

121. ELIXIR OF GENTIAN.

Fluid extract of gentian,........... 2 fluidounces.
Simple elixir,..............................14 fluidounces.
Alcohol,....................................... fluidounce.
Carbonate of magnesium,....... a sufficient quantity.

Triturate the fluid extract of gentian in a capacious mortar with carbonate of magnesium in amount sufficient to form a creamy mixture, then gradually add the simple elixir, stirring well, and filter.
Lastly, mix the filtrate with the alcohol.
Each fluidrachm of the finished elixir represents seven and one-half minims of fluid extract of gentian.

122. COMPOUND ELIXIR OF GENTIAN.

Compound fluid extract of gentian,......2 fluidounces.
Simple elixir,..........................................16 fluidounces
Carbonate of magnesium,....... .........a sufficient quantity.

Triturate the compound fluid extract of gentian with carbonate of magnesium in sufficient amount to form a creamy
mixture, then gradually add the simple elixir, and filter.
Each fluidrachm of this elixir represents the virtues of seven and one-half minims of compound fluid extract of gentian.
The National Formulary prepares this substance from the solid extract of gentian. The product is similar to that of our formula.

123. ELIXIR OF WILD GINGER.

Fluid extract of wild ginger,.... 1 fluidounce.
Fluid extract of pleurisy root,.. fluidounce.
Fluid extract of juniper berries, fluidounce.
Fluid extract of anise (or powdered anise, 120 grains),.................. fluidounce.
Fluid extract of caraway (or powdered caraway, 120 grains),. fluidounce.
Simple elixir...............................14 fluidounces.
Alcohol, ...................................... fluidounce.
Carbonate of magnesium,....... a sufficient quantity.

Triturate the mixed fluid extracts in a capacious mortar, with carbonate of magnesium in amount sufficient to form a creamy mixture, then gradually add the simple elixir, stirring well, and filter.
Lastly, mix the filtrate with the alcohol.
Each fluidrachm of the finished elixir represents about three and one-half minims of fluid extract of wild ginger, and one and threefourths each of fluid extract of pleurisy root and juniper berries. This compound was suggested in 1877, by Mr. T. F. Thorworth, in the Druggists’ Circular.

124. ELIXIR OF GLYCYRRHIZIN.

Ammoniacal glycyrrhizin,.......... 128 grains.
Simple elixir,..............................16 fluidounces.

Dissolve the glycyrrhizin in the simple elixir, and filter if necessary.
Each fluidrachm (teaspoonful) of the finished elixir contains one grain of ammoniacal glycyrrhizin. This elixir is used to disguise the bitterness of quinine; but it must be remembered that quinine will not dissolve in it, and that quinine is precipitated by ammoniacal glycyrrhizin from solutions which are not strongly acid. Hence the reason for the tastelessness of quinine under these conditions is largely due to its insoluble state. Such mixtures should be shaken before taking each dose, and under no condition should the mixture be filtered, as the quinine will then remain on the filter paper. The above formula is that of Prof. Joseph P. Remington.

125. ELIXIR OF GLYCYRRHIZIN (AROMATIC)

Coriander seed,.......................... .... 108 grains.
Caraway seed,............................. .... 108 grains.
Cinnamon,......................................... 93 grains
Star anise,........................................... 62 grains
Tonka bean,................................ ....... 62 grains
Canella,............................................... 31 grains
Nutmeg,...................................... ....... 31 grains
Cloves,......................................... ....... 31 grains
Ammoniacal glycyrrhizin,........... 620 grains
Oil of orange,..................................31 minims
Alcohol,.......................................16 fluidounces
Distilled water,...........................16 fluidounces
Simple syrup,............................. 48 fluidounces

Dissolve the oil of orange in the alcohol and add the distilled water, and, having properly moistened the mixed and powdered drugs with a portion of this menstruum, pack them in a suitable percolator and exhaust with the remainder of it. Dissolve the ammoniacal glycyrrhizin in a small amount of boiling water, and add the syrup, mix this with the percolate previously obtained, and then add of distilled water an amount sufficient to make the whole measure eighty
fluidounces. Filter if necessary.
This elixir was also devised by Prof. Joseph P. Remington, and is used as a vehicle for the administration of quinine. The remarks we have made concerning “elixir of ammoniacal glycyrrhizin” may be applied with propriety to this preparation.

126. ELIXIR OF GRINDELIA ROBUSTA.
(ELIXIR OF GRINDELIA.)

Fluid extract of grindelia robusta, 1 fluidounce.
Simple elixir,..............................15 fluidounces.
Alcohol,....................................... fluidounce.
Carbonate of magnesium,....... a sufficient quantity.

Triturate the fluid extract of grindelia in a capacious mortar with carbonate of magnesium in amount sufficient to form a creamy mixture, then gradually add the simple elixir, stirring well, and filter.
Lastly, mix the filtrate with the alcohol.
Each fluidrachm of the finished elixir represents such an amount of seven and one-half minims of fluid extract of grindelia robusta as will dissolve in the menstruum. Grindelia robusta contains a resin which is precipitated by water; hence we do not consider an elixir of this plant to be desirable.
The National Formulary adopted the foregoing strength, and we confirm that proportion. In former editions of our publication we have used twice that amount of grindelia.

127. ELIXIR OF GUARANA.

Fluid extract of guarana,.......... 3 fluidounces.
Simple elixir,..............................13 fluidounces
Carbonate of magnesium,....... a sufficient quantity.

Triturate the fluid extract of guarana in a capacious mortar with carbonate of magnesium in amount sufficient to form a creamy mixture, then gradually add the simple elixir, stirring well, and filter.
Lastly, mix the filtrate with the alcohol.
Each fluidrachm (teaspoonful) of the finished elixir represents seven and one-half minims of fluid extract of guarana, and is essentially the same as that recommended by the American Pharmaceutical Association, 1875. In the same year Mr. George W. Kennedy, through the American Journal of Pharmacy, gave a formula for this elixir, each fluidrachm of which represented fifteen grains of guarana.
The National Formulary authorizes the above proportion of guarana. In former editions of this work two fluidounces of the fluid extract were employed. Each fluidrachm represents about eleven grains of guarana.

128. ELIXIR OF GUAIACUM.
Gum guaiacum (pulverized),.2 troyounces.
Balsam of Peru,..........................2 fluidrachms.
Oil of sassafras,........................... 1 fluidrachm.
*Volatile oily spirit,.................. ............1 pint.

“Digest the gum guaiacum and balsam of Peru in the volatile oily spirit for six days, in a closely stopped vial which is now and then shaken; afterwards strain the tincture and add it to the essential oil of sassafras.”
(Edinburgh Pharmacopoeia, 1770.)

*Volatile oily spirit was made as follows: Take of—
Volatile sal-ammoniac,.............................. 8 ounces.
Essential oil of rosemary,......................... 1 ounces.
Oil of amber,................................... ............ 1 ounce.
Essence of lemon peel,...................... ............ ounce
French brandy,................................ ........1 gallons

Draw off by distillation, in the heat of a water bath, near one gallon (Edinburgh Pharmacopoeia, 1770.)

129. ELIXIR ACIDUM HALLERI.
(HALLER’S ACID ELIXIR.)

Sulphuric acid,........................... .1 troyounce.
Alcohol,.......................................3 troyounces.

Add the sulphuric acid to the alcohol, drop by drop, stirring constantly. Preserve the finished elixir in glass-stoppered bottles. This is the process of the German Pharmacopoeia, 1872, and is essentially the same as elixir acidum Dippelii, which contains one part of sulphuric acid to two parts of alcohol.

130. HELMONT’S ELIXIR.

1Any fixed alkaline salt,...........8 troyounces.
Socotrine aloes,...........................1 troyounce.
Saffron,........................................ .1 troyounce.
Myrrh,...........................................1 troyounce.
Sal-ammoniac,........................... .....6 drachms
2Mountain wine,....................... .......... 2 pints.
Macerate without heat for a week or longer, then filter
through paper.
(London Pharmacopoeia, 1770.)

l FIXED .ALKALINE SALT.—This was impure potassium carbonate. To give the definition of the New Dispensatory, 1770: “The ashes of most vegetables, steeped or boiled,in water, give out to it a saline substance, separable in a solid form by evaporating the water. This kind of salt never preexists in the vegetables, but is always generated during the burning. It is called fixt alkaline salt.”

2.Mountain wine of that day was Vinum album, Lond. Pharm., or Vinum album Hispanicum, Edinb. Pharm.

131. ELIXIR OF HELONIAS.

Compound fluid extract of helonias,
...........................................2 fluidounces.
Simple elixir,..............................14 fluidounce.
Alcohol,....................................... fluidounce.
Carbonate of magnesium,....... a sufficient quantity.

Triturate the compound fluid extract of helonias with carbonate of magnesium in sufficient amount to form a creamy
mixture, then gradually add the simple elixir, and filter. Mix the alcohol with the filtrate.
Each fluidrachm of the finished preparation will contain such proportion of seven and one-half minims of compound fluid extract of helonias as will dissolve in one fluidrachm of the menstruum.

132. HOFFMANN’S STOMACH ELIXIR.
(ELIXIR VISCERALE HOFFMANNI.)

Orange peel,...........................................6 parts.
Cassia bark,.............................................2 parts.
Carbonate of potassium,.......... ............ 1 part.
Sherry wine,............................... ..........50 parts

Macerate for eight days, express, and strain. To the colature add of—

Extract of gentian,.................................. 1 part.
Extract of wormwood,.............. ............ 1 part.
Extract of buck-bean,................. ............ 1 part.
Extract of cascarilla,................... ............ 1 part.
After repose, filter.

It forms a clear liquid of a brown color, having a peculiar, aromatic odor and a bitter taste. It should be preserved in a well-closed vessel.
(German Pharmacopoeia, 1872.)

133. ELIXIR OF HOPS.

Fluid extract of hops,................ 2 fluidounces.
Alcohol,....................................... fluidounce.
Simple elixir,..............................14 fluidounces.
Carbonate of magnesium,....... a sufficient quantity.

Triturate the fluid extract of hops in a capacious mortar with carbonate of magnesium in amount sufficient to form a creamy mixture, then gradually add the simple elixir, stirring well, and filter.
Lastly, mix the filtrate with the alcohol.
Each fluidrachm of the finished elixir represents such an amount of seven and one-half minims of fluid extract of hops as will dissolve in the menstruum. The remarks concerning compound elixir of hops may be applied to this preparation.

134. ELIXIR OF HOPS AND CHIRETTA.

Fluid extract of hops,................ 1 fluidounce.
Fluid extract chiretta,................1 fluidounce.
Simple elixir,..............................14 fluidounces.
Alcohol,....................................... fluidounce
Carbonate of magnesium,....... a sufficient quantity.

Mix the fluid extracts, and triturate in a capacious mortar with carbonate of magnesium in amount sufficient to form a creamy mixture, then gradually add the simple elixir, stirring well, and filter.
Lastly, mix the filtrate with the alcohol.
Each fluidrachm of the finished elixir represents such an amount of three and one-half minims each of fluid extract of hops and of chiretta as will dissolve in the menstruum used in its preparation.
Our remarks regarding compound elixir of hops may be applied with equal pertinence to this.

135. COMPOUND ELIXIR OF HOPS.

Fluid extract of hops,................ 2 fluidounces.
Fluid extract of orange peel,.... fluidounces.
Simple elixir,..............................14 fluidounces.
Alcohol,....................................... fluidounce
Carbonate of magnesium,....... a sufficient quantity.

Mix the fluidextracts, and triturate them in a capacious mortar with carbonate of magnesium in amount sufficient to form a creamy mixture, then gradually add the simple elixir, stirring well, and filter.
Lastly, mix the filtrate with the alcohol.
Each fluidrachm of the finished elixir represents such an amount of seven and one-half minims of fluid extract of hops as will dissolve in the menstruum.
The ingredients for the above mixture were named by the Druggists’ Circular, 1876. We do not consider an aqueous menstruum to be well adapted to the purpose of exhausting the medicinal principles of hops, hence we think that this elixir is not a desirable preparation.

136. HUFELAND’S ELIXIR.
Extract of blessed thistle,.......... troyounce.
Extract of bittersweet,................ troyounce.
Fennel water,..............................8 fluidounces.
Cherry-laurel water,..................1 fluidounce.

Mix the extracts in a mortar, and dissolve them by trituration with the mixed fennel and cherry-laurel waters, and then filter.

137. ELIXIR OF HYPOPHOSPHITES.

Hypophosphite of calcium,......... 384 grains.
Hypophosphite of sodium,..... .... 128 grains.
Hypophosphite of potassium, .... 128 grains.
Citric acid,.......................................... 30 grains.
Water,.......................................... 4 fluidounces.
Alcohol,....................................... fluidounce.
Compound spirit of cardamom, fluidounce.
Aromatic elixir, enough to make 16 fluidounces.

The hypophosphites and the citric acid are to be dissolved in the water; then the alcohol, compound spirit of cardamom, and enough aromatic elixir to make sixteen fluidounces are to be added.
Filter if necessary. Each fluidrachm contains three grains of hypophosphite of calcium and one grain each of the hypophosphites of sodium and potassium. This formula is similar to that adopted by the National Formulary.





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